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Product Name
Mouse Cndp2/Cn2 (His tag) recombinant protein
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Description
Mouse cytosolic non-specific dipeptidase(CNDP2) is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 has 2 Isoform: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 hydrolyzes a variety of dipeptides including L-carnosine and has a strong preference for Cys-Gly. It is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. It may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.
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Protein name
CNDP dipeptidase 2 (metallopeptidase M20 family)(Cndp2)
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Protein short names
Cn2
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Uniprot ID
Q9D1A2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Cndp2/Cn2 Met1-Asn475 is expressed with a 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Cndp2/Cn2 (His tag) recombinant protein
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