Anti-CNDP2 antibody

Anti-CNDP2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit monoclonal to CNDP2

IHC-P

Mouse CNDP2
Has cross-reactivity in ELISA with Human CNDP2

0610010E05Rik antibody; C76600 antibody; Cn2 antibody; CN2 antibody; Cndp2 antibody; CNDP2 antibody; CPGL antibody; Dip-2 antibody; FLJ10830 antibody; HsT2298 antibody; Pep1 antibody; Pep-1 antibody; PEPA antibody; CN2 antibody; CPGL antibody; PEPA antibody; HsT2298 antibody; HEL-S-13 antibody; Cn2 antibody; Pep1 antibody; Dip-2 antibody; Pep-1 antibody; C76600 antibody; 0610010E05Rik antibody

Rabbit IgG

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CNDP2 (rM CNDP2; NP_075638.2; Met1-Asn475).

Monoclonal

0.2 μm filtered solution in PBS with 5% trehalose

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Mouse cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.

• Bakker,SJ. et al., 2008, Diabetes  57 (12):e16; author reply e17. 
• Wanic, K. et al., 2008, Diabetes  57 (9): 2547-51.
• McDonough,CW. et al., 2009, Hum Genet 126 (2): 265-75.
• Kaur,H. et al., 2009, J Biol Chem. 284 (21):14493-502.