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Product Name
Mouse Cd27/Tnfrsf7 (Fc & His tag) recombinant protein
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Description
Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
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Protein name
CD27 antigen(Cd27)
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Protein short names
Tnfrsf7
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Uniprot ID
P41272
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Cd27/Tnfrsf7 Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Cd27/Tnfrsf7 (Fc & His tag) recombinant protein
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