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Product Name
Mouse Adipoq/Acdc/Acrp30/Apm1 (His tag) recombinant protein
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Description
Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
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Protein name
adiponectin, C1Q and collagen domain containing(Adipoq)
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Protein short names
Acdc; Acrp30; Apm1
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Uniprot ID
Q60994
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Adipoq/Acdc/Acrp30/Apm1 Glu18-Asn247 is expressed with a 6His tag at the N-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Adipoq/Acdc/Acrp30/Apm1 (His tag) recombinant protein
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