Human ADIPOQ/ACDC/ACRP30/APM1/GBP28 (His tag) recombinant protein

Human ADIPOQ/ACDC/ACRP30/APM1/GBP28 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.

adiponectin, C1Q and collagen domain containing(ADIPOQ)

ACDC; ACRP30; APM1; GBP28

Q15848

Human Cells

A DNA sequence encoding the Human ADIPOQ/ACDC/ACRP30/APM1/GBP28 Glu19-Asn244 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.