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Product Name
Mouse CD16 / FCGR3 (His Tag) recombinant protein
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Description
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor.
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Protein name
Low affinity immunoglobulin gamma Fc region receptor III
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Protein short names
FCRIIIA; CD16; FCGRIV; FCRIII; FCGAMMARIV; FCR-10; FCGR3A; FCGR3; FC Γ FCRIIIB; FCGR4; FCGRIII; IGFR3; RIII; FCG3; FC GAMMA RIII; CD16-2
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Uniprot ID
P08508
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Gene Name
Fcgr3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse FCGR3 (P08508-1) extracellular domain (Met 1-Thr 215) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse FCGR3 consists of 196 amino acids and has a predicted molecular mass of 22.6 kDa. As a result of glycosylation, the apparent molecular mass of rmFCGR3 is approximately 35-40 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized mouse FCGR3-His at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1The EC50 of biotinylated human IgG1 is 0.12-0.28 μg/ml. -
Validations
Mouse CD16 / FCGR3 Protein (His Tag) SDS-PAGE
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