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Product Name
Rat CD32b/Fc gamma RIIB/FCGR2B (His Tag) recombinant protein
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Description
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens.
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Protein name
Low affinity immunoglobulin gamma Fc region receptor II
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Protein short names
LY-M20; FCGRII; CD32; RP11-474I16.2; FCR-2; AI528646; FCR-3; LYM-1; FC[G]RII; FCG2; IGFR2; CD32B; FCRII; FCGR2A; LY-17; F630109E10RIK; FCGR2
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Uniprot ID
Q63203
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Gene Name
Fcgr2; Fcgr2b
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat FCGR2B (Q63203-1) extracellular domain (Met 1-Pro 212) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat FCGR2B comprises 192 amino acids and predicts a molecular mass of 21.9 kDa. The apparent molecular mass of the rat FCGR2B is approximately 35-40 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized human rat FCGR2B-His (Cat:500369) at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1, The EC50 of biotinylated human IgG1 is 0.3-0.8 μg/ml. -
Validations
Rat CD32b / FCGR2B Protein (His Tag) SDS-PAGE
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