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Product Name
Mouse Junctional Adhesion Molecule B (Fc Tag) recombinant protein
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Description
May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
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Protein name
Junctional adhesion molecule B
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Protein short names
VE-JAM; AU016127; VEJAM; RP23-253E17.2; 2410167M24RIK; 1110002N23RIK; JAM-IT/VE-JAM; CD322; JCAM2; JAMB; JAM-2; JAM-B; UNQ219/PRO245; C21ORF43; PRO245; 2410030G21RIK; JAM2
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Uniprot ID
Q9JI59
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Gene Name
Jam2; Vejam
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse JAM-2 (NP_076333.3) extracellular domain (Met 1-Asn 236) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse JAM-2/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 449 amino acids and has a predicted molecular mass of 50.3 kDa. rm JAM-2/Fc monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 70 % as determined by SDS-PAGE
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Activity
Measured by its ability of the immobilized protein to support the adhesion of Jurkat human leukemic T cells. When 8 x 10E4 cells/well are added to JAM2 coated plates (0.2 μg/ml and 100 μl/well), approximately 40-55% will adhere specifically after 60 minutes at 37℃.
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Validations
Mouse JAM-2 / JAM-B Protein (Fc Tag) SDS-PAGE
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