-
Product Name
Human JAM2/C21orf43/VEJAM/UNQ219/PRO245 (Fc tag) recombinant protein
- Documents
-
Description
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
-
Protein name
junctional adhesion molecule 2(JAM2)
-
Protein short names
C21orf43; VEJAM; UNQ219; PRO245
-
Uniprot ID
P57087
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human JAM2/C21orf43/VEJAM/UNQ219/PRO245 Phe29-Asn236 is expressed with a Fc tag at the C-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human JAM2/C21orf43/VEJAM/UNQ219/PRO245 (Fc tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"