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Product Name
Human JAM2/C21orf43/VEJAM/UNQ219/PRO245 (His tag) recombinant protein
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Description
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
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Protein name
junctional adhesion molecule 2(JAM2)
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Protein short names
C21orf43; VEJAM; UNQ219; PRO245
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Uniprot ID
P57087
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human JAM2/C21orf43/VEJAM/UNQ219/PRO245 Phe29-Asn236 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human JAM2/C21orf43/VEJAM/UNQ219/PRO245 (His tag) recombinant protein
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