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Product Name
Rat Junctional Adhesion Molecule A (His Tag) recombinant protein
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Description
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus (By similarity).
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Protein name
Junctional adhesion molecule A
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Protein short names
JAM-1; ESTM33; CD321; LY106; KAT; JAM-A; F11R; JAMA; 9130004G24; PAM-1; JCAM1; AA638916; JAM1; JAM; JCAM
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Uniprot ID
Q9JHY1
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Gene Name
F11r; Jam1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat F11R (Q9JHY1) (Met1-Gly238) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat F11Rcomprises 223 amino acids and predicts a molecular mass of 24.3 kDa. The apparent molecular mass of the recombinant protein is approximately 28 and 32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> (23.7+75.2) % as determined by SDS-PAGE
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Validations
Rat JAM-A / F11R Protein (His Tag) SDS-PAGE
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