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Sus scrofa (Pig) IL-10 (Pig) recombinant protein

Cat.#: 500998

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Product Information

  • Product Name
    Sus scrofa (Pig) IL-10 (Pig) recombinant protein
  • Documents
  • Description
    Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
  • Protein name
    Interleukin-10
  • Protein short names
    GVHDS; TGIF; IL10; CSIF; RP11-262N9.1; MGC126450; IL10A; IL-10; MGC126451; AL513351.1
  • Uniprot ID
    Q29055
  • Gene Name
    IL10
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the porcine IL10 (Q29055) (Ser19-Asn175) was expressed with an initial Met at the N-terminal.
  • Protein Species
    Sus scrofa (Pig)
  • Molecular weight
    The recombinant porcine IL10 consists of 158 amino acids and has a predicted molecular mass of 18.2 kDa. The apparent molecular mass of it is approximately 18 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    1. Immobilized porcineIL10 at 10 μg/ml (100 μl/well) can bind Cynomolgus IL10RA-Fc (Cat:504750), The EC50 of Cynomolgus IL10RA-Fc (Cat:504750) is 0.14-0.34 μg/ml.
    2. Measured in a cell proliferation assay using MC/9-2 mouse mast cells. The ED50 for this effect is typically 1-5 ng/mL.
  • Validations

    Sus scrofa (Pig) IL10 / Interleukin-10 Protein SDS-PAGE

    Sus scrofa (Pig) IL10 / Interleukin-10 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"