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  • Human TFAM Recombinant protein (GST tag)

Human TFAM Recombinant protein (GST tag)

Cat.#: 513518

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human TFAM Recombinant protein (GST tag)
  • Documents
  • Description
    Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. {PubMed:1737790, PubMed:19304746, PubMed:20410300, PubMed:22037171, PubMed:22037172, PubMed:22841477}.
  • Protein name
    Transcription factor A, mitochondrial
  • Protein short names
    TCF6; TCF6L2
  • Uniprot ID
    Q00059
  • Gene Name
    TFAM; TCF6; TCF6L2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-246 aa encoded by BC126366 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human TFAM SDS-PAGE

    Recombinant human TFAM SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"