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Product Name
Human STAT3/APRF (His tag) recombinant protein
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Description
Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
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Protein name
signal transducer and activator of transcription 3(STAT3)
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Protein short names
APRF
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Uniprot ID
P40763
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human STAT3/APRF Met1-Asn175 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human STAT3/APRF (His tag) recombinant protein
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