Anti-STAT3 (4C8) Mouse antibody

Cat.#: 168119

Special Price 123.9 USD

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Product Information

  • Product Name
    Anti-STAT3 (4C8) Mouse antibody
  • Documents
  • Description
    STAT3 (4C8) Mouse monoclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat, Monkey, Hamster
  • Alternative names
    1110034C02Rik;Acute Phase Response Factor;Acute-phase response factor;APRF;AW109958;DNA binding protein APRF;FLJ20882;HIES;MGC128731; MGC16063;MGC93551;Signal transducer and activator of transcription 3 (acute-phase response factor);Signal transducer and antibody
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant human STAT3 protein fragments expressed in E.coli
  • Clonality
    Monoclonal
  • Formulation
    Ascites containing with 0.03% Proclin300 and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of STAT3 in CHO-K1,C6,3T3,K562,CEM,Jurkat,Hela,MCF7,COS7,293T,A431 and A549 cell lysates using STAT3 mouse mAb (1:1000 diluted).Predicted band size:88KDa.Observed band size:88KDa.

    Western blot detection of STAT3 in CHO-K1,C6,3T3,K562,CEM,Jurkat,Hela,MCF7,COS7,293T,A431 and A549 cell lysates using STAT3 mouse mAb (1:1000 diluted).Predicted band size:88KDa.Observed band size:88KDa.

  • Background
    Swiss-Prot Acc.P40763.Signal transducer and transcription activator that mediates cellular responses to interleukins,KITLG/SCF and other growth factors.May mediate cellular responses to activated FGFR1,FGFR2,FGFR3 and FGFR4.Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.Activated by IL31 through IL31RA.Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity.Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G by similarity.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"