Human KIM-1/TIM1/HACVR1 recombinant protein

Cat.#: 503829

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Product Information

  • Product Name
    Human KIM-1/TIM1/HACVR1 recombinant protein
  • Documents
  • Description
    Human HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
  • Protein name
    Hepatitis A virus cellular receptor 1
  • Protein short names
    TIM; TIMD1; HAVCR-1; TIM-1; RP23-31K14.2; KIM1; HAVCR1; HAVCR; TIM1; TIMD-1; CANIS LUPUS FAMILIARIS; KIM-1; AI503787
  • Uniprot ID
    Q96D42
  • Gene Name
    HAVCR1; KIM1; TIM1; TIMD1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human KIM1 extracellular domain (AAC39862.1) (Ser 21-Gly 290) with a C-terminal polyhistidine tag was expressed and purified.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human KIM1 comprises 278 amino acids and predicts a molecular mass of 30 kDa. It migrates with the molecular weight in the range of 90-110 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Human KIM-1 / TIM1 / HAVCR1 Protein SDS-PAGE

    Human KIM-1 / TIM1 / HAVCR1 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"