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Product Name
Human KIM-1/TIM1/HACVR1 (His & Fc Tag) recombinant protein
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Description
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.
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Protein name
Hepatitis A virus cellular receptor 1
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Protein short names
KIM-1; CANIS LUPUS FAMILIARIS; AI503787; TIMD-1; TIM1; HAVCR; HAVCR1; KIM1; RP23-31K14.2; TIM-1; HAVCR-1; TIMD1; TIM
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Uniprot ID
Q96D42
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Gene Name
HAVCR1; KIM1; TIM1; TIMD1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human KIM1 extracellular domain (AAC39862.1) (Ser 21-Gly 290) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human KIM1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 515 amino acids and predicts a molecular mass of 57 kDa. As a result of glycosylation, the apparent molecular mass of KIM1/Fc monomer is approximately 120-140 kDa in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human KIM-1 / TIM1 / HAVCR1 Protein (His & Fc Tag) SDS-PAGE
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