• Human IL6 recombinant protein (Native)

Human IL6 recombinant protein (Native)

Cat.#: 514884

Special Price 543.2 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human IL6 recombinant protein (Native)
  • Documents
  • Description
    Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
  • Protein name
    cDNA FLJ61423, highly similar to Interleukin-6
  • Protein short names
    BSF2,HGF,HSF,IFNB2,IL-6,Interleukin-6
  • Uniprot ID
    B4DVM1
  • Gene Name
    cDNA FLJ61423, highly similar to Interleukin-6
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human IL6 (NP_000591.1) (Val30-Met212) was expressed with an initial Met at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL6 consists of 184 amino acids and has a calculated molecular mass of 20.9 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human IL6/IL-6/Interleukin-6 Protein 14107

    Human IL6/IL-6/Interleukin-6 Protein 14107

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"