Human IL6/IFNB2 recombinant protein

Human IL6/IFNB2 recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is important to the biological activity of the molecule. Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.

interleukin 6(IL6)

IFNB2

P05231

E. coli

A DNA sequence encoding the Human IL6/IFNB2 Pro29-Met212 is expressed.

Human

>95% as determined by SDS-PAGE.