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Product Name
Human IL10RB/CRFB4/D21S58/D21S66 (His tag) recombinant protein
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Description
IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
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Protein name
interleukin 10 receptor subunit beta(IL10RB)
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Protein short names
CRFB4; D21S58; D21S66
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Uniprot ID
Q08334
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IL10RB/CRFB4/D21S58/D21S66 Met20-Ser220 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IL10RB/CRFB4/D21S58/D21S66 (His tag) recombinant protein
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