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Human IGF2BP3 Recombinant protein (GST tag)

Cat.#: 508956

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human IGF2BP3 Recombinant protein (GST tag)
  • Documents
  • Description
    RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. {PubMed:16541107, PubMed:23640942}.
  • Protein name
    Insulin-like growth factor 2 mRNA-binding protein 3
  • Protein short names
    IMP3; KOC1; VICKZ3
  • Uniprot ID
    O00425
  • Gene Name
    IGF2BP3; IMP3; KOC1; VICKZ3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IGF2BP3 (XP_047275738.1) 295-634 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human IGF2BP3 SDS-PAGE

    Recombinant human IGF2BP3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"