-
Product Name
Human HMGB1/HMG1 recombinant protein
- Documents
-
Description
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
-
Protein name
high mobility group box 1(HMGB1)
-
Protein short names
HMG1
-
Uniprot ID
P09429
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human HMGB1/HMG1 Pro92-Val176 is expressed with a MARI tag at the N-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human HMGB1/HMG1 recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"