Human HMGB1/HMG1 (His tag) recombinant protein

Cat.#: 518224

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Product Information

  • Product Name
    Human HMGB1/HMG1 (His tag) recombinant protein
  • Documents
  • Description
    High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
  • Protein name
    high mobility group box 1(HMGB1)
  • Protein short names
    HMG1
  • Uniprot ID
    P09429
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human HMGB1/HMG1 Gly2-Glu215 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human HMGB1/HMG1 (His tag) recombinant protein

    Human HMGB1/HMG1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"