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Human FADD Recombinant protein (GST tag)

Cat.#: 507716

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human FADD Recombinant protein (GST tag)
  • Documents
  • Description
    Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. {PubMed:16762833, PubMed:19118384, PubMed:20935634, PubMed:21109225}.
  • Protein name
    FAS-associated death domain protein
  • Protein short names
    MORT1
  • Uniprot ID
    Q13158
  • Gene Name
    FADD; MORT1; GIG3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human FADD (NP_003815.1) 1-208 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human FADD SDS-PAGE

    Recombinant human FADD SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"