• Human ARRB1/ARR1 (His tag) recombinant protein

Human ARRB1/ARR1 (His tag) recombinant protein

Cat.#: 518020

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Product Information

  • Product Name
    Human ARRB1/ARR1 (His tag) recombinant protein
  • Documents
  • Description
    β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.
  • Protein name
    arrestin beta 1(ARRB1)
  • Protein short names
    ARR1
  • Uniprot ID
    P49407
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ARRB1/ARR1 Met1-Arg418 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ARRB1/ARR1 (His tag) recombinant protein

    Human ARRB1/ARR1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"