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Product Name
Human ARRB1/ARR1 (His tag) recombinant protein
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Description
β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.
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Protein name
arrestin beta 1(ARRB1)
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Protein short names
ARR1
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Uniprot ID
P49407
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ARRB1/ARR1 Met1-Arg418 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ARRB1/ARR1 (His tag) recombinant protein
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