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Product Name
Human AIF1/G1/IBA1 (His tag) recombinant protein
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Description
Allograft Inflammatory Factor 1 (AIF1) contains two EF-hand domains and exists as a homodimer. AIF1 can be detected in T-lymphocytes and peripheral blood mononuclear cells. AIF1 functions as actin-binding protein that enhances membrane ruffling and RAC activation and can enhance the actin-bundling activity of LCP1. In addition, AIF1 plays a role in RAC signaling and in phagocytosis and may also in macrophage activation and function. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes and plays a role in vascular inflammation.
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Protein name
allograft inflammatory factor 1(AIF1)
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Protein short names
G1; IBA1
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Uniprot ID
P55008
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human AIF1/G1/IBA1 Ser2-Pro147 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human AIF1/G1/IBA1 (His tag) recombinant protein
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