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Product Name
Human IBA1/AIF1 (His Tag) recombinant protein
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Description
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
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Protein name
Allograft inflammatory factor 1
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Protein short names
PROTEIN G1; IONIZED CALCIUM-BINDING ADAPTER MOLECULE 1; AI607846; ALLOGRAFT INFLAMMATORY FACTOR-1 SPLICE VARIANT HARA-1; AIF1; G1; AIF-1; IBA1IONIZED CALCIUM BINDING ADAPTER MOLECULE 1; TESTIS SPECIFIC; IRT-1; INTERFERON GAMMA RESPONSIVE TRANSCRIPT; ALLOGRAFT INFLAMMATORY FACTOR 1; IBA1; IRT1; DADB-70P7.8; D17H6S50E
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Uniprot ID
P55008
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Gene Name
AIF1; G1; IBA1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human AIF1 (P55008-1) (Met1-Pro147) was expressed with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human AIF1 consists of 162 amino acids and predicts a molecular mass of 18.5 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human IBA1 / AIF1 Protein (His Tag) SDS-PAGE
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