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Product Name
Anti-Iba1 Rabbit antibody
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Description
Iba1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human, Mouse, Rat
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Alternative names
G1; Iba1; AIF-1; AI607846; D17H6S50E antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Iba1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/20-1/500
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Validations
Western blot detection of Iba1 in C6,3T3,Hela cell lysates using Iba1 Rabbit pAb(1:1000 diluted).Predicted band size:17kDa.Observed band size:17kDa.
Immunohistochemistry of Iba1 in paraffin-embedded Human colon cancer tissue using Iba1 Rabbit pAb at dilution 1/20
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Background
Swiss-Prot Acc.O70200.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"