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Product Name
Mouse PSMA / FOLH1 (His Tag) recombinant protein
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Description
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides (By similarity). In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate.
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Protein name
Glutamate carboxypeptidase 2
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Protein short names
FGCP; MGC141397; GCPII; GCP2; MOPSM; NAALADASE; MGCP; NAALAD1; PSMA; FOLH1; FOLH; PSM
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Uniprot ID
O35409
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Gene Name
Folh1; Mopsm; Naalad1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse FOLH1 (NP_058050.3) extracellular domain (Ile 44-Ala 752) was expressed, fused with a polyhistidine tag at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse FOLH1 consists of 725 amino acids and has a calculated molecular mass of 81.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 88 % as determined by SDS-PAGE
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Validations
Mouse PSMA / FOLH1 Protein (His Tag) SDS-PAGE
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