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Product Name
Human PSMA / FOLH1 (His Tag) recombinant protein
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Description
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.
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Protein name
Glutamate carboxypeptidase 2
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Protein short names
NAALADASE; GCP2; MOPSM; MGC141397; GCPII; FGCP; PSM; FOLH; NAALAD1; PSMA; FOLH1; MGCP
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Uniprot ID
Q04609
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Gene Name
FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human FOLH1 (NP_004467.1) (Lys44-Ala750) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human FOLH1 consists 725 amino acids and predicts a molecular mass of 81.7 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Human PSMA / FOLH1 Protein (His Tag)
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