Anti-PSMA Rabbit antibody
PSMA Rabbit monoclonal antibody
PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; NAALAdase antibody
Antigen: A synthetic peptide of human PSMA
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
Western blot detection of PSMA in 3T3 cell lysates using PSMA Rabbit mAb(1:1000 diluted).Predicted band size:84kDa.Observed band size:100kDa.
Swiss-Prot Acc.Q04609.Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.MiscellaneousPSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease.
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