GHR Polyclonal Antibody

Cat.#: 162236

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Product Information

  • Product Name
    GHR Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to GHR
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    GHR antibody; GHBP antibody; GHIP antibody; growth hormone receptor antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-260 of human GHR (NP_001229328.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - GHR Polyclonal Antibody

    Western blot - GHR Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using GHR antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 30s.

  • Background
    Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity).; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.; Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"