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Product Name
Rat Growth Hormone Receptor / GHR / GHBP (Fc Tag) recombinant protein
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Description
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.
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Protein name
Growth hormone receptor
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Protein short names
GHR; GROWTH HORMONE RECEPTOR; AA986417; GHIP; GHR/BP; GHBP
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Uniprot ID
P16310
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Gene Name
Ghr
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat GHR (P16310-1) (Met1-Arg265) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat GHR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 488 amino acids and has a predicted molecular mass of 55.4 kDa. The apparent molecular mass of the protein is approximately 66 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Rat Growth Hormone Receptor / GHR / GHBP Protein (Fc Tag) SDS-PAGE
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