FOLR1 antibody

FOLR1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FOLR1 Mouse Monoclonal antibody. Positive WB detected in HeLa cells, MCF-7 cells. Observed molecular weight by Western-blot: 36-38 kDa

ELISA, WB

Human; other species not tested.

Adult folate binding protein antibody; FBP antibody; Folate receptor 1 antibody; folate receptor 1 (adult) antibody; Folate receptor alpha antibody; Folate receptor antibody; adult antibody; FOLR antibody; FOLR1 antibody; FR alpha antibody; KB cells FBP antibody; MOv18 antibody

Mouse IgG1

This antibody was obtained by immunization of FOLR1 recombinant protein (Accession Number: NM_016725). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Folate receptor 1 (FOLR1), also known as folate receptor alpha or adult folate-binding protein (FBP), is a 38-kDa glycoprotein belonging to the folate receptor family (PMID:15094207; 23528302). The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung, kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer, non-small cell lung cancer, breast cancer, kidney cancer and high-grade osteosarcoma (PMID: 23528302; 23357463).