Anti-Folate Binding Protein Rabbit antibody

Cat.#: 168606

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Product Information

  • Product Name
    Anti-Folate Binding Protein Rabbit antibody
  • Documents
  • Description
    Folate Binding Protein Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    FBP; FOLR antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Folate Binding Protein
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000-1/2000

    IHC: 1/200

  • Validations

    Western blot detection of Folate Binding Protein in Hela cell lysates using Folate Binding Protein Rabbit mAb(1:1000 diluted).Predicted band size:30kDa.Observed band size:40kDa.

    Western blot detection of Folate Binding Protein in Hela cell lysates using Folate Binding Protein Rabbit mAb(1:1000 diluted).Predicted band size:30kDa.Observed band size:40kDa.

  • Background
    Swiss-Prot Acc.P15328.Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"