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Product Name
Anti-Folate Binding Protein Rabbit antibody
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Description
Folate Binding Protein Rabbit monoclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human, Mouse, Rat
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Alternative names
FBP; FOLR antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Folate Binding Protein
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/2000
IHC: 1/200
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Validations
Western blot detection of Folate Binding Protein in Hela cell lysates using Folate Binding Protein Rabbit mAb(1:1000 diluted).Predicted band size:30kDa.Observed band size:40kDa.
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Background
Swiss-Prot Acc.P15328.Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"