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Product Name
Rat B7-H3/CD276 (His Tag) recombinant protein
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Description
Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. May play a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells (By similarity).
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Protein name
CD276 antigen
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Protein short names
AU016588; B7-H3; B7RP-2; CD276; 6030411F23RIK; 4IG-B7-H3; PSEC0249; B7H3
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Uniprot ID
Q7TPB4
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Gene Name
Cd276; B7h3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat CD276 (Q7TPB4)(Met1-Phe244) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat CD276 comprises 227 amino acids and predicts a molecular mass of 25 kDa. The apparent molecular mass of the recombinant protein is approximately 43 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Rat B7-H3 / CD276 Protein (His Tag) SDS-PAGE
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