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Anti-SOX2 (2A10) Mouse antibody

Cat.#: 168183

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Product Information

  • Product Name
    Anti-SOX2 (2A10) Mouse antibody
  • Documents
  • Description
    SOX2 (2A10) Mouse monoclonal antibody
  • Tested applications
    WB, FC, ICC/IF
  • Species reactivity
    Mouse
  • Alternative names
    ANOP3;cb236;Delta EF2a;lcc;MCOPS3;MGC148683;MGC2413;RGD1565646;Sex determining region Y box 2;SOX 2;Sox2;SOX2_HUMAN;SRY (sex determining region Y) box 2;SRY box containing gene 2;SRY related HMG box 2;SRY related HMG box gene 2;SRY-box 2;Transcription fac antibody
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant mouse Sox2 protein fragments expressed in E.coli
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    ;ICC: 1/150;Other 1/1000

  • Validations

    Western blot detection of Sox2 in mES cell lysates using Sox2 antibody(1:1000 diluted).Predicted band size:35KDa,Observed band size:35KDa.Kindly provided by Dr. Qintong Li at the College of Life Sciences, Sichuan University

    Western blot detection of Sox2 in mES cell lysates using Sox2 antibody(1:1000 diluted).Predicted band size:35KDa,Observed band size:35KDa.Kindly provided by Dr. Qintong Li at the College of Life Sciences, Sichuan University

    Flow Cytometry analysis of F9 cells stained with Sox2 (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.

    Flow Cytometry analysis of F9 cells stained with Sox2 (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.

    Western blot detection of Sox2 in F9 cell lysates using Sox2 mouse mAb (1:1000 diluted).Predicted band size:35KDa.Observed band size:35KDa.

    Western blot detection of Sox2 in F9 cell lysates using Sox2 mouse mAb (1:1000 diluted).Predicted band size:35KDa.Observed band size:35KDa.

    Immunocytochemistry of COS7 cells using anti-Sox2 mouse mAb diluted 1:150.

    Immunocytochemistry of COS7 cells using anti-Sox2 mouse mAb diluted 1:150.

  • Background
    Swiss-Prot Acc.P48432.Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"