Human SOX2 Recombinant protein (GST tag)

Human SOX2 Recombinant protein (GST tag)

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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). {, PubMed:18035408}.

Transcription factor SOX-2

P48431

SOX2

E. coli

59-118 aa encoded by NM_003106 was inserted into PGEX-4T vector

Human

Not tested.