Cart 2

Anti-SOX2 (3D8) Mouse antibody

Cat.#: 168503

Size:

Special Price 441.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-SOX2 (3D8) Mouse antibody
  • Documents
  • Description
    SOX2 (3D8) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF
  • Species reactivity
    Human
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human SOX2 expressed in E. Coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    IHC: 1/200 - 1/1000

    ICC: 1/200 - 1/1000

    ELISA: 1/10000

  • Validations

    Western blot analysis using SOX2 mAb against HEK293 (1) and SOX2(AA: 2-317)-hIgGFc transfected HEK293 (2) cell lysate.

    Western blot analysis using SOX2 mAb against HEK293 (1) and SOX2(AA: 2-317)-hIgGFc transfected HEK293 (2) cell lysate.

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.

    Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red

    Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red

  • Background
    Swiss-Prot Acc.P48431.This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"