NovoPro
Cart 2
  • Anti-Phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) Rabbit antibody

Anti-Phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) Rabbit antibody

Cat.#: 169073

Size:

Special Price 441.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-Phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) Rabbit antibody
  • Documents
  • Description
    Phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) Rabbit polyclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human Phospho-ERK1 (Y204) + ERK2 (Y187)
  • Clonality
    Polyclonal antibody
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500-1/2000

    IP: 1/50

  • Validations

    Western blot analysis of Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187) expression in A431 cell lysate treated with EGF.

    Western blot analysis of Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187) expression in A431 cell lysate treated with EGF.

  • Background
    Swiss-Prot Acc.P27361,P28482.Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"