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  • Anti-p44 MAPK (ERK1) (1E5) Mouse antibody

Anti-p44 MAPK (ERK1) (1E5) Mouse antibody

Cat.#: 169103

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Product Information

  • Product Name
    Anti-p44 MAPK (ERK1) (1E5) Mouse antibody
  • Documents
  • Description
    p44 MAPK (ERK1) (1E5) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat, Monkey
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human MAPK3 expressed in E. Coli.
  • Clonality
    Monoclonal antibody
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    IHC: 1/200 - 1/1000

    ICC: 1/200 - 1/1000

    FC: 1/200 - 1/400

    ELISA: 1/10000

  • Validations

    Western blot detection of ERK1 in PC12,K562 and Hela cell lysates using ERK1 mouse mAb (dilution 1:500).Predicted band size:44KDa.Observed band size:44KDa.

    Western blot detection of ERK1 in PC12,K562 and Hela cell lysates using ERK1 mouse mAb (dilution 1:500).Predicted band size:44KDa.Observed band size:44KDa.

  • Background
    Swiss-Prot Acc.P27361.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"