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Product Name
Anti-Nucleophosmin (2D9) Mouse antibody
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Description
Nucleophosmin (2D9) Mouse monoclonal antibody
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Tested applications
WB, ChIP
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Species reactivity
Human, Mouse
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Alternative names
B23;MGC104254;NMP1;NO38;NPM 1;NPM;NPM_HUMAN;NPM1;Nucleolar Phosphoprotein B23;Nucleolar protein NO38;Nucleophosmin (nucleolar phosphoprotein B23 numatrin);Nucleophosmin; Nucleophosmin/B23.2;Nucleophosmin/nucleoplasmin family member 1;Nucleoplasmin Family antibody
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Isotype
IgG1
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Preparation
Antigen: Purified recombinant full length of human NPM1 protein expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
;ICC: 1/200
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Validations
Western blot detection of NPM1 in Hela,Jurkat and 3T3 cell lysates using NPM1 mouse mAb (1:1000 diluted).Predicted band size:33KDa.Observed band size:38KDa.
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Background
Swiss-Prot Acc.P06748.Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"