Anti-LIN28A (2C1) Mouse antibody

Cat.#: 168454

Special Price 123.9 USD

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Product Information

  • Product Name
    Anti-LIN28A (2C1) Mouse antibody
  • Documents
  • Description
    LIN28A (2C1) Mouse monoclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse
  • Alternative names
    CSDD1;FLJ12457;LIN 28;Lin-28A;LIN28;LIN28A;LN28A_HUMAN;Protein lin-28 homolog A;ZCCHC1; Zinc finger CCHC domain-containing protein 1. antibody
  • Isotype
    Mouse IgG2a
  • Preparation
    Antigen: Purified recombinant human LIN28A protein fragments expressed in E.coli
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of LIN28 in NTERA and F9 cell lysates using LIN28A mouse mAb (1:1000 diluted).Predicted band size:26KDa.Observed band size:26KDa.

    Western blot detection of LIN28 in NTERA and F9 cell lysates using LIN28A mouse mAb (1:1000 diluted).Predicted band size:26KDa.Observed band size:26KDa.

    Western blot detection of LIN28A in LIN28B and LIN28A recombinant antigen fragments and using LIN28A mouse mAb (1:1000 diluted).

    Western blot detection of LIN28A in LIN28B and LIN28A recombinant antigen fragments and using LIN28A mouse mAb (1:1000 diluted).

  • Background
    Swiss-Prot Acc.Q9H9Z2.Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.
  • References
    • Primordial Dwarfism Gene Maintains Lin28 Expression to Safeguard Embryonic Stem Cells from Premature Differentiation

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"