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Product Name
Anti-IKB alpha Rabbit antibody
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Description
IKB alpha Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, IP
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human IKB alpha
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/2000
IHC: 1/50-1/200
ICC/IF: 1/50-1/200
IP: 1/30
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Validations
Western blot analysis of IKB alpha expression in HeLa cell lysate.
Immunofluorescent analysis of Hela cells, using IKB alpha Antibody .
Immunohistochemical analysis of paraffin-embedded mouse stomach, using IKB alpha Antibody.
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Background
Swiss-Prot Acc.P25963.NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.
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References
- Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-κB pathway
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"