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Product Name
Anti-HSP90 alpha (6H7) Mouse antibody
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Description
HSP90 alpha (6H7) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat, Monkey
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Alternative names
Heat shock 86 kDa; Heat shock 90kDa protein 1 alpha; Heat shock protein 90kDa alpha (cytosolic) class A member 1; heat shock protein 90kDa alpha (cytosolic) antibody; class A member 2; Heat shock protein HSP 90-alpha; HS90A_HUMAN; HSP 86; HSP 86; HSP 86; HSP86; Hs antibody
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Isotype
IgG1
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Preparation
Antigen: Purified recombinant human Hsp90 alpha protein fragments expressed in E.coli
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide 1mg/ml BSA and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of Hsp90 alpha in R Brain,Jurkat,CHO-K1,COS7,C6,3T3 and Hela cell lysates using Hsp90 alpha mouse mAb (1:1000 diluted). Predicted band size:90KDa. Observed band size:90KDa.
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Background
Swiss-Prot Acc.P07900.HSP90A a molecular chaperone of the heat shock protein 90 family. Has ATPase activity. Known to interact with a wide variety of proteins including steroid hormone receptors, neuropeptide Y, FKBP51/54, and FKBP52. G protein-coupled receptor kinases are stabilized by interacting with HSP 90. Hsp70 and Hsp90 promote tau solubility and tau binding to microtubules, reducing insoluble tau.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"