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Product Name
Anti-Hsp90 (4B6) Mouse antibody
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Description
Hsp90 (4B6) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
D6S182;FLJ26984;FLJ31884;Heat shock 86 kDa;heat shock 90kDa protein 1 alpha;Heat shock protein 90kDa alpha cytosolic class A member 1;Heat shock protein 90kDa alpha cytosolic class B member 1; Heat shock protein HSP 90 alpha;Heat shock protein HSP 90 beta antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Purified recombinant human HSP90AA1 protein fragments expressed in E.coli
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/2000
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Validations
Western blot detection of Hsp90 in Hela,3T3,C6,K562 and A549 cell lysates using Hsp90 mouse mAb (1:2000 diluted).Exposion time: 4min.Predicted band size:90KDa.Observed band size:90KDa.
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Background
Swiss-Prot Acc.P07900.Molecular chaperone that promotes the maturation,structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.Undergoes a functional cycle that is linked to its ATPase activity.This cycle probably induces conformational changes in the client proteins,thereby causing their activation.Interacts dynamically with various co-chaperones that modulate its substrate recognition,ATPase cycle and chaperone function.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"