Anti-CREB (2F6) Mouse antibody

Cat.#: 168372

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Product Information

  • Product Name
    Anti-CREB (2F6) Mouse antibody
  • Documents
  • Description
    CREB (2F6) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF
  • Species reactivity
    Human, Mouse, Rat, Monkey
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human CREB1 expressed in E. Coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    IHC: 1/200 - 1/1000

    ICC: 1/200 - 1/1000

    ELISA: 1/10000

  • Validations

    Immunohistochemical analysis of paraffin-embedded prostate cancer tissues (left) and submaxillary tumor tissues (right) using CREB1 mouse mAb with DAB staining.

    Immunohistochemical analysis of paraffin-embedded prostate cancer tissues (left) and submaxillary tumor tissues (right) using CREB1 mouse mAb with DAB staining.

    Western blot detection of CREB in Jurkat,A549,MCF7,C6 and Hela cell lysates using CREB mouse mAb (1:3000 diluted).Predicted band size:43KDa.Observed band size:43KDa.

    Western blot detection of CREB in Jurkat,A549,MCF7,C6 and Hela cell lysates using CREB mouse mAb (1:3000 diluted).Predicted band size:43KDa.Observed band size:43KDa.

    Immunofluorescence analysis of Hela cells using CREB1 mouse mAb (green). Red

    Immunofluorescence analysis of Hela cells using CREB1 mouse mAb (green). Red

  • Background
    Swiss-Prot Acc.P16220.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. (provided by RefSeq)
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"