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Product Name
Anti-CREB Rabbit antibody
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Description
CREB Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
CREB; CREB-1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human CREB
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/20
FC: 1/20
IP: 1/20
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Validations
Immunohistochemistry of CREB in paraffin-embedded Human lung cancer tissue using CREB Rabbit pAb at dilution 1/20
Western blot detection of CREB in Hela cell lysates using CREB Rabbit pAb(1:1000 diluted).Predicted band size:37KDa.Observed band size:43KDa.
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Background
Swiss-Prot Acc.P16220.Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.SitesFeature keyPosition(s)Description
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"