Anti-CREB (1E9) Mouse antibody

Cat.#: 168228

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Product Information

  • Product Name
    Anti-CREB (1E9) Mouse antibody
  • Documents
  • Description
    CREB (1E9) Mouse monoclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human, Rat
  • Alternative names
    Active transcription factor CREB; cAMP response element binding protein 1; cAMP response element binding protein; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; CREB; CREB-1; CREB1; CREB1_HUMAN; Cyclic AMP-responsive antibody
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant human CREB protein fragments expressed in E.coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascites containing with 0.03% Proclin300 and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of CREB in Jurkat,A549,MCF7,C6 and Hela cell lysates using CREB mouse mAb(dilution 1:1000).Predicted band size:46kDa.Observed band size:43kDa.

    Western blot detection of CREB in Jurkat,A549,MCF7,C6 and Hela cell lysates using CREB mouse mAb(dilution 1:1000).Predicted band size:46kDa.Observed band size:43kDa.

  • Background
    Swiss-Prot Acc.P16220.This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"