Anti-Cofilin Rabbit antibody

Cat.#: 167694

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Product Information

  • Product Name
    Anti-Cofilin Rabbit antibody
  • Documents
  • Description
    Cofilin Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Cofilin
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/50

    ICC/IF: 1/50

    FC: 1/200

  • Validations

    Western blot detection of Cofilin in A549,MCF-7,293T cell lysates using Cofilin Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

    Western blot detection of Cofilin in A549,MCF-7,293T cell lysates using Cofilin Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

  • Background
    The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"